Sanja Mijatovic Selected Research

saquinavir-NO

1/2017	HIV-protease inhibitors for the treatment of cancer: Repositioning HIV protease inhibitors while developing more potent NO-hybridized derivatives?
10/2015	The NO-modified HIV protease inhibitor as a valuable drug for hematological malignancies: Role of p70S6K.
10/2012	Therapeutic potential of nitric oxide-modified drugs in colon cancer cells.
8/2012	Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells.
3/2012	Saquinavir-NO-targeted S6 protein mediates sensitivity of androgen-dependent prostate cancer cells to TRAIL.
7/2011	Cytotoxic and immune-sensitizing properties of nitric oxide-modified Saquinavir in iNOS-positive human melanoma cells.
2/2011	In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells.
5/2009	The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt.

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Sanja Mijatovic Research Topics

Disease

18	Neoplasms (Cancer) 07/2021 - 05/2009
7	Melanoma (Melanoma, Malignant) 10/2019 - 09/2008
4	Colonic Neoplasms (Colon Cancer) 05/2019 - 10/2012
4	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 02/2011
2	Experimental Melanoma 07/2021 - 05/2009
2	Adenocarcinoma 07/2021 - 01/2019
2	Glioma (Gliomas) 07/2021 - 07/2007
2	Neoplasm Metastasis (Metastasis) 01/2019 - 07/2014
2	Breast Neoplasms (Breast Cancer) 01/2016 - 07/2014
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 09/2013 - 08/2006
1	Wounds and Injuries (Trauma) 01/2022
1	Hypertrophic Cicatrix (Hypertrophic Scar) 01/2022
1	Ulcer 01/2022
1	Cicatrix (Scar) 01/2022
1	Carcinoma (Carcinomatosis) 07/2021
1	Colorectal Neoplasms (Colorectal Cancer) 07/2021
1	Glioblastoma (Glioblastoma Multiforme) 09/2018
1	Kaposi Sarcoma (Kaposi's Sarcoma) 01/2017
1	Neuroblastoma 01/2016
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2015
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2015
1	Hematologic Neoplasms (Hematological Malignancy) 10/2015
1	Carcinogenesis 08/2012
1	Hepatitis 08/2009
1	Drug-Related Side Effects and Adverse Reactions 05/2009
1	Necrosis 07/2007
1	Fibrosarcoma 07/2007

Drug/Important Bio-Agent (IBA)

8	saquinavir-NOIBA 01/2017 - 05/2009
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2019 - 08/2006
6	Pharmaceutical PreparationsIBA 05/2019 - 02/2011
5	Saquinavir (Invirase)FDA Link 10/2012 - 05/2009
4	HIV Protease InhibitorsIBA 10/2019 - 05/2009
2	Lopinavir FDA Link 10/2019 - 09/2018
2	Cytostatic AgentsIBA 05/2019 - 01/2019
2	Hormones (Hormone)IBA 07/2014 - 02/2011
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2012 - 03/2011
2	Antineoplastic Agents (Antineoplastics)IBA 08/2012 - 08/2009
2	Protease Inhibitors (Protease Inhibitor)IBA 08/2012 - 02/2011
1	CollagenIBA 01/2022
1	Alcian BlueIBA 01/2022
1	C.I. direct red 80IBA 01/2022
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 07/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2019
1	ProdrugsIBA 05/2019
1	Ketoprofen (Orudis)FDA LinkGeneric 05/2019
1	EstersIBA 05/2019
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2019
1	Androgen Receptors (Androgen Receptor)IBA 01/2019
1	Celecoxib (Celebrex)FDA Link 01/2019
1	IsoflavonesIBA 01/2019
1	SteroidsIBA 01/2019
1	Prostate-Specific Antigen (Semenogelase)IBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 01/2019
1	Serine Proteases (Serine Protease)IBA 01/2019
1	Cisplatin (Platino)FDA LinkGeneric 04/2017
1	LeukotrienesIBA 01/2017
1	EnzymesIBA 01/2017
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2017
1	Arachidonic Acid (Vitamin F)IBA 01/2017
1	ErbB Receptors (EGF Receptor)IBA 01/2016
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 10/2015
1	Mechanistic Target of Rapamycin Complex 1IBA 07/2014
1	Estrogen Receptor alphaIBA 07/2014
1	GoldIBA 06/2014
1	undecylprodigiosinIBA 06/2014
1	Interleukin-2 (IL2)IBA 09/2013
1	apotransferrinIBA 09/2013
1	MTOR InhibitorsIBA 10/2012
1	Antiviral Agents (Antivirals)IBA 10/2012
1	Acetic Acid (Vinegar)FDA LinkGeneric 10/2012
1	2,2'- (hydroxynitrosohydrazono)bis- ethanamineIBA 08/2012
1	AndrogensIBA 03/2012
1	Proteins (Proteins, Gene)FDA Link 03/2012
1	CaspasesIBA 04/2010
1	N- acetyl- S- (alpha- methyl- 4- (2- methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl esterIBA 08/2009
1	Concanavalin AIBA 08/2009
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 05/2009
1	3-phenyl-4,5-dihydro-5-isoxazole acetic acidIBA 09/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2007
1	aloe emodinIBA 07/2007
1	AnthraquinonesIBA 07/2007
1	CytokinesIBA 07/2007
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 07/2007
1	Interleukin-17 (Interleukin 17)IBA 08/2006

Therapy/Procedure

5	Therapeutics 01/2017 - 03/2011
2	Drug Therapy (Chemotherapy) 11/2011 - 05/2009
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2022
1	Ligation 04/2012
1	Radiotherapy 11/2011